Els ICREA

Els professors d'investigació ICREA formen una comunitat dinàmica de científics i investigadors de totes les àrees del coneixement, que contribueixen al progrés de la humanitat amb els seus estudis, interpretacions i preguntes. Entreu i descobriu-ne els increïbles descobriments i troballes:

Prieto Simón, Beatriz

Institut Català d'Investigació Química (ICIQ)

CLOSE

Prieto Simón, Beatriz
Research Professor at
Institut Català d'Investigació Química (ICIQ)
Engineering Sciences
view profile

Research interests

Her research aims to deliver versatile nanoarchitectures to build bespoke diagnostics, by harnessing high-precision fabrication methods, and advances in engineering surface functionalities. Their assembly in hierarchical structures, with tuneable electrochemical properties and surface chemistry, and displayed bioreceptors, is strongly intertwined with the material’s functions. Her interest lies in gathering new knowledge on the relationship between nanoarchitecture/displayed functionalities and function, to design sensors underpinning personalised clinical management of infections. The next generation of diagnostics is expected to meet the needs for host-immune response assessment, pathogen-associated and antibiotic resistance biomarkers detection, and monitoring of antibiotic levels. The potential of these tools to guide antibiotics choice is foreseen as a key driver toward effective treatment, protecting patients from antibiotics adverse effects, and dwindling antibiotic resistance.

Key words
Diagnosis of infectious diseases, bioinspired nanochannel platforms, biosensors, nanoporous materials, chemical functionalisation, novel electrochemical transducers, wearable biosensors

ORCID
: 0000-0001-8016-1565

RESEARCHER ID
: B-1508-2017
Prieto Vives, Pilar

Universitat Pompeu Fabra (UPF)

CLOSE

Prieto Vives, Pilar
Research Professor at
Universitat Pompeu Fabra (UPF)
Humanities
view profile

Research interests

My main research goal is to understand the role of prosody and co-speech gestures in human communication from a crosslinguistic, developmental, and cognitive perspective. Three important strands of this research include: (a) to incorporate this knowledge into semantic models of language that model the interface areas with other components; (b) to empirically investigate how humans process prosodic and gestural patterns in combination with speech; and (c) to investigate the cognitive and developmental benefits of prosody and gesture in different areas, such as first and second language acquisition, as well as communication training for language impaired and non-impaired populations. The social significance of this research topic is high, as ICT training procedures based on prosodic and gestural awareness can be proven valuable to improve language abilities in populations with neurodevelopmental disorders characterized by impaired social interaction.

Key words
Prosody, Gesture, Semantics, Acquisition

ORCID
: orcid.org/0000-0001-8175-1081

RESEARCHER ID
: E-7390-2013
Pruneri, Valerio

Institut de Ciències Fotòniques (ICFO)

CLOSE

Pruneri, Valerio
Research Professor at
Institut de Ciències Fotòniques (ICFO)
Engineering Sciences
view profile

Research interests

The Optoelectronics group (OptoGroup) at the Institute of Photonic Sciences (ICFO) studies and develops new advanced materials, devices and systems for optical telecommunication, sensing and quantum industry. In particular, the main driving is to carry out research which bridges academia and industry, by developing fundamental ideas which will have an impact on commercial products.

Key words
Photonics, Optoelectronics, Optical materials, Optical engineering, Fibre Optics, Optical communication, Optical sensing, Quantum cryptography
Przulj, Natasa

Barcelona Supercomputing Center - Centro Nacional de Supercomputación (BSC-CNS)

CLOSE

Przulj, Natasa
Research Professor at
Barcelona Supercomputing Center - Centro Nacional de Supercomputación (BSC-CNS)
Life & Medical Sciences
view profile

Research interests

Molecular and clinical data integration for precision medicine: patient stratification, biomarker discovery, drug re-purposing, drug discovery, disease re-classification. Data analytics, modeling, fusion, dynamics, applied to clinical, molecular and biological data. Algorithms for uncovering molecular mechanisms of disease from systems-level “omics” data. Molecular networks: interactome evolution, dynamics, alignment, function prediction. Large-scale economic data analysis, fusion and modeling the dynamics of economic systems. Computational graph theory, algorithms, artificial inteligence, models.

Key words
computational biology and bioinformatics; molecular networks; methods for molecular and clinical data integration for precision medicine; data analytics, modeling, fusion, dynamics

ORCID
: orcid.org/0000-0002-1290-853X
Puigmartí Luis, Josep

Universitat de Barcelona (UB)

CLOSE

Puigmartí Luis, Josep
Research Professor at
Universitat de Barcelona (UB)
Experimental Sciences & Mathematics
view profile

Research interests

Self-assembly can be described as a dynamic process present in nature that has long been used for the evolution of living organisms, but is still scarcely understood by modern science. The main reason being that self-assembly is generally studied under equilibrium conditions. Despite the remarkable progress made in materials engineering, the quest for a technology to study and kinetically control self-assembled processes is still incomplete. Like in nature, only through kinetic controlled conditions we can achieve materials with a rationalized function and efficiency; a result that will open new horizons in nanotechnology. Therefore, the research activities of his group are centred on accomplishing an extraordinary kinetic control over self-assembly by controlling the fluid flow phenomena of reagents at the micro and nanoscale.

Key words
Microfluidic Technologies, Flow Chemistry, Chemical Engineering, Supramolecular Chemistry, Surface Chemistry, Molecular Nanoscience, Materials Engineering, Functional Materials, Nanotechnology

ORCID
: 0000-0002-7510-9815

RESEARCHER ID
: A-5302-2015
Pujol Onofre, Aurora

Institut d'Investigació Biomèdica de Bellvitge (IDIBELL)

CLOSE

Pujol Onofre, Aurora
Research Professor at
Institut d'Investigació Biomèdica de Bellvitge (IDIBELL)
Life & Medical Sciences
view profile

Research interests

Our mission is to improve disease management of rare brain disorders through precision medicine. This spans the whole spectrum from genomic diagnosis to disease-modifying treatments. A first research line revolves around adrenoleukodystrophy (ALD), made popular by the movie "Lorenzo's Oil". We are integrating multiomic approaches to gain insights into pathomechanisms for drug target and biomarker identification. These involve the control of redox, metabolic and mitochondrial homeostasis. Preclinical tests using mouse models for ALD yielded four licensed patents, four phase II/III clinical trials, and four Orphan Drug Designations. Currently, a phase II-III against placebo clinical trial is funded by the Spanish National Institutes of Health. A second research line applies clinical and functional genomics, including development of computational algorithms, for solving undiagnosed cases of brain rare disorders and expanding scientific knowledge by discovering novel genetic causes of brain malfunction.

Key words
Clinical Genomics, Integrative multiomics, Systems neuroscience, Rare disease, Leukodystrophies, Adrenoleukodystrophy, Disease Modeling

ORCID
: 0000-0002-9606-0600

RESEARCHER ID
: N-4990-2014