Institut Hospital del Mar d'Investigacions Mèdiques (IMIM)
Life & Medical Sciences
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Research interests
Given my initial background in Physics and Applied Mathematics, I have developed Signal Processing methods for the analysis of complex electrophysiology data. In particular, I developed a ‘spike sorting’ algorithm to identify the activity of single neurons that outperformed previous algorithms and that is currently used by several laboratories worldwide [Neural Comp 2004]. The use of this algorithm allowed me to discover a new type of neuron in the human brain, so called “Concept Cells” or “Jennifer Aniston neurons”, which fire selectively to specific concepts [Nature 2005]. In following studies, we showed that these neurons form and store memories [Neuron 2015; Nat. Comm. 2016; Nat. Comm. 2018; Cell 2019], and based on these data, I have proposed that memory coding in the human hippocampus is completely different to what has been described in other species and can be the basis of cognitive abilities uniquely developed in humans [Cell 2017; Science 2019; Cell 2019; TiCS 2020].