Patents

ICREA selects researchers based solely on their scientific achievements. However, excellent science often leads to the invention of new and amazing technologies and solutions. When that happens, ICREA fully supports the exploitation of these opportunities.

Our ICREA research professors are working in different Universities and Research Centres. On account of this, ownership of any intellectual or industrial property is always shared between ICREA and the host institution. To make negotiations as fast and conclusive as possible, host institutions are entitled to explore and engage in technology transfer activities on behalf of ICREA when opportunities arise. ICREA supports the exploitation efforts and offers advice throughout the process.

Please have a look at our current technologies and contact ICREA to learn more about them.

Engineering Sciences
Sistema y método de generación de haces acústicos confocales de vórtice con superposición espaciotemporal.

JIMÉNEZ GONZÁLEZ, Noé; STALIUNAS, Kestutis; CAMARENA FEMENIA, Francisco;
CSIC

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Sistema y método de generación de haces acústicos confocales de vórtice con superposición espaciotemporal.

JIMÉNEZ GONZÁLEZ, Noé; STALIUNAS, Kestutis; CAMARENA FEMENIA, Francisco;
CSIC

La presente invención se enmarca en el campo de la acústica y, más concretamente, en el campo de la generación y la localización de haces acústicos tridimensionales para interaccionar y manipular sin contacto la materia, mediante campos acústicos.
Filing date: 22 Jul, 2020

P202030766, ES2811650
Engineering Sciences
Polymersomes functionalised with multiple ligands

Giuseppe Battaglia
UCL Business ltd

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Polymersomes functionalised with multiple ligands

Giuseppe Battaglia
UCL Business ltd

The present invention is directed to a nanoparticle or microparticle for binding to the surface of a cell, wherein the nanoparticle or microparticle comprises (i) multiple different ligand types on its external surface which are capable of binding to different respective receptor types on said cell surface, and (ii) a polymer brush on its external surface. The present invention is further directed to pharmaceutical compositions comprising a plurality of nanoparticles or microparticles of the invention, medical uses of such nanoparticles or microparticles, and a vaccine comprising such nanoparticles or microparticles.
Filing date: 7 Jul, 2020

WO2020144467A1
Engineering Sciences
Antireflective multilayer article with nanostructures

PRUNERI, Valerio; ROMBAUT, Juan; MAZUMDER Prantik
ICREA

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Antireflective multilayer article with nanostructures

PRUNERI, Valerio; ROMBAUT, Juan; MAZUMDER Prantik
ICREA

The present invention relates to antireflective multilayer article with self-cleaning nanostructures and to process to obtain it. The antireflective multilayer of the invention is paricularly useful for photovoltaic cells, laser device, display screens and light detection and ranging (LIDAR) system.
Filing date: 22 Jun, 2020

EP20383093.0
Life & Medical Sciences
Chimeric antigen receptors specific for P95HER2 and uses thereof

Joaquín Arribas López; Irene Rius Ruiz; Macarena Romás Alonso; Alena Gros Vidal; Carlos Alberto Fajardo Calderón
VHIO

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Chimeric antigen receptors specific for P95HER2 and uses thereof

Joaquín Arribas López; Irene Rius Ruiz; Macarena Romás Alonso; Alena Gros Vidal; Carlos Alberto Fajardo Calderón
VHIO

La presente invención se refiere a un receptor de antígeno quimérico (CAR) capaz de 5 dirigirse a células que expresan p95HER2. La invención también se refiere a un fragmento variable de cadena sencilla (ScFv), a un dominio de unión a antígeno y a un anticuerpo o fragmento de anticuerpo del mismo capaz de unirse al antígeno p95HER2. Además, la presente invención se refiere a un conjugado anticuerpo-fármaco (ADC) que comprende un agente terapéutico y un anticuerpo o dominio de unión a antígeno 10 específico para p95HER2. La invención también se refiere a un método de diagnóstico de cáncer y a una composición farmacéutica para su uso en un método de prevención o tratamiento del cáncer que comprenden el CAR y/o el dominio de unión a antígeno o el anticuerpo de la invención.
Filing date: 12 Jun, 2020

EP20382457.8 - PCT/EP2021/064383 - 17/999,769
Engineering Sciences
MULTI-COLOR IMAGING

Melike Lakadamyali, Maria Garcia-Parajo; Pablo Gomez
FUNDACIO INSTITUTDE CIENCIES FOTONIQUES, Barcelona (ES)

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MULTI-COLOR IMAGING

Melike Lakadamyali, Maria Garcia-Parajo; Pablo Gomez
FUNDACIO INSTITUTDE CIENCIES FOTONIQUES, Barcelona (ES)

The disclosure relates to a method and an imaging device for multi-color imaging using frequency-modulated illumination. The method comprises a step of providing electromagnetic radiation with a plurality of different wavelengths, comprising a step of modulating each wavelength with a different modulation frequency, a step of illuminating a target with the modulated electromagnetic radiation, in particular for excitation of a target, a step of sensing electromagnetic radiation emitted from the target, in particular the luminescence, more in particular the fluorescence, and a step of processing the data obtained in the step of sensing
Filing date: 28 May, 2020

Licenced date: 29 Mar, 2022

US11,287,628B2
Engineering Sciences
Production of nanoparticles and microparticles

Giuseppe Battaglia Aroa Duro Castano
UCL Business ltd

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Production of nanoparticles and microparticles

Giuseppe Battaglia Aroa Duro Castano
UCL Business ltd

The present invention is directed to a method for producing nanoparticles and microparticles composed of peptide- or peptoid-containing amphiphilic polymers. The method is simple, capable of achieving high yields, and can be tailored to produce a range of industrially and therapeutically useful structures including vesicles, micelles and hydrogels. The present invention also provides related hydrogels and vesicles having beneficial properties such an ability to degrade and release a payload in response to external stimuli.
Filing date: 1 May, 2020

WO2020225538A1
Life & Medical Sciences
Genetically reprogrammed Mycoplasma bacteria and uses thereof

Maria Lluch, Luis Serrano
Centre for Genomic Regulation (CRG)

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Genetically reprogrammed Mycoplasma bacteria and uses thereof

Maria Lluch, Luis Serrano
Centre for Genomic Regulation (CRG)

20382288.7 Abandoned PCT/EP2021/059142 Abandoned
Filing date: 8 Apr, 2020

21718089.2 - EP4133115
Life & Medical Sciences
CD22 Targeting-moiety for the treatment of B-cell acute lymphoblastic Leukemia (B-ALL).

MENÉNDEZ BUJÁN, Mr. Pablo; VELASCO HERNÁNDEZ, Ms. Talía; ROMINA ZANETTI, Ms. Samanta; ENGEL ROCAMORA, Mr. Pablo; SÁNCHEZ MARTÍNEZ, Mr. Diego; GUTIERREZ AGÜERA, Mr. Francisco
IJC

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CD22 Targeting-moiety for the treatment of B-cell acute lymphoblastic Leukemia (B-ALL).

MENÉNDEZ BUJÁN, Mr. Pablo; VELASCO HERNÁNDEZ, Ms. Talía; ROMINA ZANETTI, Ms. Samanta; ENGEL ROCAMORA, Mr. Pablo; SÁNCHEZ MARTÍNEZ, Mr. Diego; GUTIERREZ AGÜERA, Mr. Francisco
IJC

The present invention provides therapeutics for the treatment of CD22-positive cancers such as B-cell acute lymphoblastic eukemia (B-ALL). In particular, the present invention provides an anti-CD22 monoclonal antibody whose F(AB')2, particularly the scFv fragment, can target the CD22 antigen, for use in the treatment of CD22-positive cancers.
Filing date: 11 Mar, 2020

Licenced date: 16 Jul, 2020

EP20382175.6
Engineering Sciences
Method to photo-capture CO2 with perovskite oxide compounds

Pérez Tomás, Mr. Amador; Rubio Lorente, Mr. Carles; Sauthier, Mr. Guillaume; David, Mr. Jeremy; Vales Castro, Mr. Pablo; Arbiol Cobos, Mr. Jordi; Santiso López, Mr. Jose; Catalan Bernabé, Mr. Gustau
ICN2

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Method to photo-capture CO2 with perovskite oxide compounds

Pérez Tomás, Mr. Amador; Rubio Lorente, Mr. Carles; Sauthier, Mr. Guillaume; David, Mr. Jeremy; Vales Castro, Mr. Pablo; Arbiol Cobos, Mr. Jordi; Santiso López, Mr. Jose; Catalan Bernabé, Mr. Gustau
ICN2

The present application refers to a method for CO2 capture wherein light, particularly ultraviolet illumination, greatly improves the amount of CO2 captured on engineered perovskite oxide compounds. By a photorefractive phenomenon under near ultraviolet illumination, ionized defects are created at the surface of B-site defective oxide perovskites which act as additional CO2 trapping centres. The present method can be implemented at a temperature between -10ºC and 80ºC, and is cyclable, i.e. the perovskite oxide compounds can be regenerated by heat and used for subsequent CO2 capture.
Filing date: 30 Dec, 2019

PCT/EP2020/088044
Engineering Sciences
Material que absorbe radiación electromagnética de longitudes de onda entre 300nm i 18 micras y aplicaciones

Sepúlveda Martínez, Borja; Alvarez Sánchez, Mar; Güell i Grau, Pau; Nogués Sanmiguel, Josep; Zhi, Li
CSIC- 53%

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Material que absorbe radiación electromagnética de longitudes de onda entre 300nm i 18 micras y aplicaciones

Sepúlveda Martínez, Borja; Alvarez Sánchez, Mar; Güell i Grau, Pau; Nogués Sanmiguel, Josep; Zhi, Li
CSIC- 53%

Filing date: 11 Dec, 2019

P201931100

Patents

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Sistema y método de generación de haces acústicos confocales de vórtice con superposición espaciotemporal.

Sistema y método de generación de haces acústicos confocales de vórtice con superposición espaciotemporal.

Polymersomes functionalised with multiple ligands

Polymersomes functionalised with multiple ligands

Antireflective multilayer article with nanostructures

Antireflective multilayer article with nanostructures

Chimeric antigen receptors specific for P95HER2 and uses thereof

Chimeric antigen receptors specific for P95HER2 and uses thereof

MULTI-COLOR IMAGING

MULTI-COLOR IMAGING

Production of nanoparticles and microparticles

Production of nanoparticles and microparticles

Genetically reprogrammed Mycoplasma bacteria and uses thereof

Genetically reprogrammed Mycoplasma bacteria and uses thereof

CD22 Targeting-moiety for the treatment of B-cell acute lymphoblastic Leukemia (B-ALL).

CD22 Targeting-moiety for the treatment of B-cell acute lymphoblastic Leukemia (B-ALL).

Method to photo-capture CO2 with perovskite oxide compounds

Method to photo-capture CO2 with perovskite oxide compounds

Material que absorbe radiación electromagnética de longitudes de onda entre 300nm i 18 micras y aplicaciones

Material que absorbe radiación electromagnética de longitudes de onda entre 300nm i 18 micras y aplicaciones

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